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Image Search Results
Journal: Scientific Reports
Article Title: Lattice light sheet imaging of membrane nanotubes between human breast cancer cells in culture and in brain metastases
doi: 10.1038/s41598-017-11223-y
Figure Lengend Snippet: Membrane nanotubes form connections between MDA-231 cells in culture. ( a , b ) Representative lattice light-sheet image of MDA-231 cells visualized by a GFP-tagged membrane marker, illustrating nanotubes interconnecting with other MDA-231 cells and contacting the coverglass. See also Movie . ( a ) is a maximum intensity z-projection (top view) of the imaging volume, and ( b ) shows an orthogonal (side) view of the same volume. ( c , d ) Histograms plot the distributions of lengths of nanotubes that interconnect MDA-231 cells ( c , n = 98 nanotubes from 16 imaging fields) and those that contact the cover glass ( d ) 113 nanotubes). Insets in ( c , d ) are transverse linescan profiles showing the widths of nanotubes that interconnect MDA-231 cells (n = 6, mean FWHM 466 ± 31 nm) and those that contact the coverglass (n = 6, mean FWHM 423 ± 15 nm).
Article Snippet:
Techniques: Membrane, Marker, Imaging